CN128: A New Orally Active Hydroxypyridinone Iron Chelator-Reference-Cited by-同舟云学术

CN128: A New Orally Active Hydroxypyridinone Iron Chelator

Published:2020-03-25 Issue:8 Volume:63 Page:4215-4226
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Wenteng¹^ORCID,Yuan Xin²,Li Zhi¹,Lu Zidong³,Kong Sisi¹,Jiang Huidi¹^ORCID,Du Houbing⁴,Pan Xiuhong⁴,Nandi Manasi³,Kong Xiaole³,Brown Kathryn³,Liu Zudong²,Zhang Guolin¹,Hider Robert C.³,Yu Yongping¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang Province, China

2. Hangzhou Zede Pharma-Tech Co. Ltd., Hangzhou 311121, Zhejiang Province, China

3. Institute of Pharmaceutical Science, Franklin-Wilkins Building, King’s College London, 150 Stamford Street, SE1 9NH London, UK

4. Suzhou Xishan Zhongke Drug R&D Co. Ltd., Suzhou 215104, Jiangsu Province, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Alzheimer's and Aging Research Center

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00137

Reference41 articles.

1. Iron Metabolism

2. Hemochromatosis

3. Current issues with blood transfusions in sickle cell disease

4. Mechanism of Iron Toxicity

5. Insulin sensitivity and β-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test

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