Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate-Reference-Cited by-同舟云学术

Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate

Published:2015-10-15 Issue:21 Volume:58 Page:8584-8600
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Junfeng¹,Zhang Xiang¹,Jin Hongjun¹,Fan Jinda¹,Flores Hubert¹,Perlmutter Joel S.¹,Tu Zhude¹

Affiliation:

1. Department of Radiology and ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States

Funder

National Institute of Neurological Disorders and Stroke

National Institute of Mental Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01205

Reference50 articles.

1. Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

2. Isolation and characterization of PDE10A, a novel human 3′, 5′-cyclic nucleotide phosphodiesterase

3. Cloning and Characterization of a Novel Human Phosphodiesterase That Hydrolyzes Both cAMP and cGMP (PDE10A)

4. Striatum- and testis-specific phosphodiesterase PDE10A

5. Immunohistochemical Localization of Phosphodiesterase 10A in Multiple Mammalian Species

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