Preliminary PET Imaging of Microtubule-Based PET Radioligand [<sup>11</sup>C]MPC-6827 in a Nonhuman Primate Model of Alzheimer’s Disease-Reference-Cited by-同舟云学术

Preliminary PET Imaging of Microtubule-Based PET Radioligand [¹¹C]MPC-6827 in a Nonhuman Primate Model of Alzheimer’s Disease

Published:2023-09-19 Issue:20 Volume:14 Page:3745-3751
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Bhoopal Bhuvanachandra¹^ORCID,Gollapelli Krishna Kumar¹,Damuka Naresh¹,Miller Mack¹,Krizan Ivan¹,Bansode Avinash¹,Register Thomas²,Frye Brett M.²,Kim Jeongchul¹,Mintz Akiva³,Orr Miranda⁴,Craft Suzanne⁴,Whitlow Christopher¹,Lockhart Samuel N.⁴^ORCID,Shively Carol A.²,Solingapuram Sai Kiran Kumar¹^ORCID

Affiliation:

1. Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States

2. Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States

3. Department of Radiology, Columbia University School of Medicine, New York, New York 10032, United States

4. Department of Gerontology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States

Funder

U.S. Department of Health and Human Services

Alzheimer's Disease Research Center, Wake Forest School of Medicine

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00527

Reference64 articles.

1. The Role of the Microtubule Cytoskeleton in Neurodevelopmental Disorders

2. The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

3. Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs

4. Microtubules, Axonal Transport, and Neuropathy

5. Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimers Disease and Related Tauopathies

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