Design, Synthesis, and Structure–Activity Relationship of Novel LSD1 Inhibitors Based on Pyrimidine–Thiourea Hybrids As Potent, Orally Active Antitumor Agents-Reference-Cited by-同舟云学术

Design, Synthesis, and Structure–Activity Relationship of Novel LSD1 Inhibitors Based on Pyrimidine–Thiourea Hybrids As Potent, Orally Active Antitumor Agents

Published:2015-02-06 Issue:4 Volume:58 Page:1705-1716
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ma Li-Ying¹,Zheng Yi-Chao¹,Wang Sai-Qi¹,Wang Bo¹,Wang Zhi-Ru¹,Pang Lu-Ping¹,Zhang Miao¹,Wang Jun-Wei¹,Ding Lina¹,Li Juan¹,Wang Cong¹,Hu Biao¹,Liu Ying¹,Zhang Xiao-Dan¹,Wang Jia-Jia¹,Wang Zhi-Jian¹,Zhao Wen¹,Liu Hong-Min¹

Affiliation:

1. Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, and School of Pharmaceutical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China

Funder

Ministry of Education of the People's Republic of China

National Natural Science Foundation of China

Young Teacher Foundation, Zhengzhou University

Education Department of Henan Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00037

Reference59 articles.