Discovery of 1,2,4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling-Reference-Cited by-同舟云学术

Discovery of 1,2,4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling

Published:2024-08-19 Issue: Volume: Page:
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

He Zhang-Xu¹²,Gao Ge²,Qiao Hui²,Dong Guan-jun²^ORCID,Dan Zengyangzong²,Li Ya-lan²,Qi Yu-ruo²,Zhang Qian²,Yuan Shuo³,Liu Hong-Min²,Dong Jianzeng⁴,Zhao Wen²^ORCID,Ma Li-Ying²⁵⁶^ORCID

Affiliation:

1. Pharmacy College, Henan University of Chinese Medicine, 450046 Zhengzhou, PR China

2. State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China

3. Henan Children’s Hospital, Zhengzhou Children’s Hospital, Children’s Hospital Affiliated to Zhengzhou University, Zhengzhou 450018, China

4. Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China

5. China Meheco Topfond Pharmaceutical Co., Zhumadian 463000, China

6. Key Laboratory of Cardiocerebrovascular Drugs, Zhumadian 463000, Henan Province, China

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00713

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