DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors
Author:
Affiliation:
1. Platform Technology & Science, GlaxoSmithKline, Winter Street, Waltham, Massachusetts 02451, United States
2. Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01898
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1. Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
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