Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example-Reference-Cited by-同舟云学术

Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example

Published:2015-11-30 Issue:23 Volume:58 Page:9287-9295
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rombouts Frederik J. R.¹,Tovar Fulgencio²,Austin Nigel³,Tresadern Gary,Trabanco Andrés A.

Affiliation:

1. Neuroscience-Medicinal Chemistry, Janssen Research & Development, Janssen Pharmaceutica N.V., Turnhoutseweg 30, B-2340 Beerse, Belgium

2. Villapharma Research S.L., Parque Tecnológico de Fuente Álamo. Ctra. El Estrecho-Lobosillo, Km. 2.5- Av. Azul 30320 Fuente Álamo de Murcia, Murcia, Spain

3. Discovery Sciences, Janssen Research & Development, Janssen Pharmaceutica N.V., Turnhoutseweg 30, B-2340 Beerse, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01088

Reference33 articles.

1. Bioisosteres in Medicinal Chemistry

2. Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

3. Identification of target-specific bioisosteric fragments from ligand–protein crystallographic data

4. Bioisosterism: A Rational Approach in Drug Design

5. Bioisosterism: A Useful Strategy for Molecular Modification and Drug Design

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