Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors-Reference-Cited by-同舟云学术

Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors

Published:2016-01-08 Issue:2 Volume:59 Page:733-749
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yogo Takatoshi¹,Nagamiya Hiroyuki¹,Seto Masaki¹,Sasaki Satoshi¹,Shih-Chung Huang²,Ohba Yusuke¹,Tokunaga Norihito¹,Lee Gil Nam³,Rhim Chul Yun³,Yoon Cheol Hwan³,Cho Suk Young³,Skene Robert⁴,Yamamoto Syunsuke¹,Satou Yousuke¹,Kuno Masako¹,Miyazaki Takahiro¹,Nakagawa Hideyuki¹,Okabe Atsutoshi¹,Marui Shogo¹,Aso Kazuyoshi¹,Yoshida Masato¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan

2. Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States

3. Chemizon, 3F Dongbang Rental Building, 333-1 Sangdaewon-Dong, Jungwon-Gu, Seongnam-Si, Kyunggi-Do 462-120, Korea

4. Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01857

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