Evaluation and Removal of Production Process Constraints in the Synthesis of 3,5-Dibromopyrazole
Author:
Affiliation:
1. Pfizer Research and Development, Groton, Connecticut 06340, United States
2. Pfizer Research and Development, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00309
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3. Long, J. K.; Ma, H.; Marshall, E. A.; Sharpe, P. L.; Ding, A. X. Fungicidal Pyrazoles. WIPO Patent WO2012030922A1, 2012.
4. Cao, Y.; Liu, X.; Mao, J.; Xu, Z. Methods for the Preparation of 5-Bromo-2-(3-Chloro-Pyridin-2-yl)-2H-Pyrazole-3-Carboxylic Acid. WIPO Patent WO2021076835 A1, 2021.
5. Benzyne and related systems: an ab initio molecular orbital approach
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