Development of a Highly Potent D2/D3 Agonist and a Partial Agonist from Structure–Activity Relationship Study of N6-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Implication in the Treatment of Parkinson’s Disease-Reference-Cited by-同舟云学术

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Development of a Highly Potent D2/D3 Agonist and a Partial Agonist from Structure–Activity Relationship Study of N6-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Implication in the Treatment of Parkinson’s Disease

Published:2015-11-30 Issue:23 Volume:58 Page:9179-9195
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Das Banibrata¹,Vedachalam Seenuvasan¹,Luo Dan¹,Antonio Tamara²,Reith Maarten E. A.²³,Dutta Aloke K.¹

Affiliation:

1. Department of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48202, United States

2. Department of Psychiatry, New York University, New York, New York 10016, United States

3. Department of Biochemistry and Molecular Pharmacology, New York University, New York, New York 10016, United States

Funder

National Institute of Neurological Disorders and Stroke

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01031

Reference64 articles.

1. Diagnostic Criteria for Parkinson Disease

2. Neuroprotection in Parkinson Disease

3. The scientific and clinical basis for the treatment of Parkinson disease (2009)

4. Update on Parkinson Disease

5. Molecular Pathways of Neurodegeneration in Parkinson's Disease

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