Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia-Reference-Cited by-同舟云学术

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Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia

Published:2022-09-28 Issue:19 Volume:65 Page:13436-13451
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Wen¹²^ORCID,Wang Chunping²,Liu Zhikun²,Gou Shaohua¹²^ORCID

Affiliation:

1. Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, Jiangsu, P. R. China

2. Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, Jiangsu, P. R. China

Funder

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01355

Reference35 articles.

1. Emerging Therapies for Recurrent Pericarditis: Interleukin‐1 inhibitors

2. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease

3. Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

4. Regulation of immunity and inflammation by hypoxia in immunological niches

5. Role of mitochondrial quality surveillance in myocardial infarction: From bench to bedside

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1. A Lysosome-Targeting hNEU1 Inhibitor Treats Myocardial Infarction: A Potential Therapeutic Breakthrough;Journal of Medicinal Chemistry;2024-09-10

2. Hypoxia-Activated Theragnostic Prodrugs (HATPs): Current State and Future Perspectives;Pharmaceutics;2024-04-19

3. Single‐Component Dual‐Functional Autoboost Strategy by Dual Photodynamic and Cyclooxygenase‐2 Inhibition for Lung Cancer and Spinal Metastasis;Advanced Science;2024-01-15

4. Dual-target inhibitors based on COX-2: a review from medicinal chemistry perspectives;Future Medicinal Chemistry;2023-12

5. Discovery of Efficient Hypoxia-Targeted NO Donor Compounds to Alleviate Hypoxia Cardiac Disease;Journal of Medicinal Chemistry;2023-11-16

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