Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41580-020-0227-y.pdf
Reference227 articles.
1. Pouyssegur, J. & López-Barneo, J. Hypoxia in health and disease. Mol. Asp. Med. 47–48, 1–2 (2016).
2. Taylor, C. T., Doherty, G., Fallon, P. G. & Cummins, E. P. Hypoxia-dependent regulation of inflammatory pathways in immune cells. J. Clin. Invest. 126, 3716–3724 (2016).
3. Semenza, G. L. Hypoxia-inducible factors in physiology and medicine. Cell 148, 399–408 (2012).
4. Keith, B., Johnson, R. S. & Simon, M. C. HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression. Nat. Rev. Cancer 12, 9–22 (2011).
5. Kaelin, W. G. et al. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 30, 393–402 (2008). Together with Semenza (2012), this review provides an excellent outline of the regulation and importance of HIFs in physiology and diseases.
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