Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One-Reference-Cited by-同舟云学术

Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One

Published:2022-07-11 Issue:14 Volume:65 Page:9507-9530
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Salerno Alessandra¹^ORCID,Seghetti Francesca¹^ORCID,Caciolla Jessica¹^ORCID,Uliassi Elisa¹^ORCID,Testi Eleonora¹,Guardigni Melissa²,Roberti Marinella¹^ORCID,Milelli Andrea²^ORCID,Bolognesi Maria Laura¹^ORCID

Affiliation:

1. Department of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy

2. Department for Life Quality Studies, Alma Mater Studiorum - University of Bologna, Corso d’Augusto 237, 47921 Rimini, Italy

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Universit? di Bologna

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00302

Reference151 articles.

1. New Chemical Modalities and Strategic Thinking in Early Drug Discovery

2. Drug Interaction Studies of Therapeutic Proteins or Monoclonal Antibodies

3. A comprehensive map of molecular drug targets

4. How many drug targets are there?

5. Targeting the Undruggable Proteome: The Small Molecules of My Dreams

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