Design, Biological Evaluation, and Computer-Aided Analysis of Dihydrothiazepines as Selective Antichlamydial Agents

Author:

de Campos Luana Janaína1,Seleem Mohamed A.1ORCID,Feng Jiachen1,Pires de Oliveira Kelly Mari2,de Andrade dos Santos João Víctor3,Hayer Shivdeep4,Clayton Jonathan B.4567,Kathi Sharvath8,Fisher Derek J.8,Ouellette Scot P.9,Conda-Sheridan Martin1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

2. Faculty of Biological and Environmental Science, Federal University of Grande Dourados, Dourados, MS 79804-970, Brazil

3. Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS 79804-970, Brazil

4. Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska 68182, United States

5. Department of Food Science and Technology, University of Nebraska─Lincoln, Lincoln, Nebraska 68588, United States

6. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

7. Nebraska Food for Health Center, University of Nebraska─Lincoln, Lincoln, Nebraska 68508, United States

8. School of Biological Sciences, Southern Illinois University, Carbondale, Illinois 62901, United States

9. Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

Funder

NIH Office of the Director

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

University of Nebraska Medical Center

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference118 articles.

1. Chlamydia trachomatis: the Persistent Pathogen

2. CDC. New CDC Analysis Shows Steep and Sustained Increases in STDs in Recent Years, 2018. https://www.cdc.gov/media/releases/2018/p0828-increases-in-stds.html (accessed Dec 07, 2021).

3. CDC. Sexually Transmitted Disease Surveillance, 2019, 2019. https://www.cdc.gov/std/statistics/2019/default.htm (accessed Nov 29, 2021).

4. Estimating the Direct Medical Costs and Productivity Loss of Outpatient Chlamydia and Gonorrhea Treatment

5. Chlamydial eye infections: Current perspectives

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