Molecular Characterization of the ClpC AAA+ ATPase in the Biology of Chlamydia trachomatis-Reference-Cited by-同舟云学术

Molecular Characterization of the ClpC AAA+ ATPase in the Biology of Chlamydia trachomatis

Published:2023-04-25 Issue:2 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Pan Stefan¹,Jensen Aaron A.²,Wood Nicholas A.²^ORCID,Henrichfreise Beate³,Brötz-Oesterhelt Heike¹⁴^ORCID,Fisher Derek J.⁵^ORCID,Sass Peter¹⁴^ORCID,Ouellette Scot P.²^ORCID

Affiliation:

1. Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany

2. Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA

3. Institute for Pharmaceutical Microbiology, University of Bonn, Bonn, Germany

4. Cluster of Excellence-Controlling Microbes to Fight Infections, Tübingen, Germany

5. School of Biological Sciences, Southern Illinois University Carbondale, Carbondale, Illinois, USA

Abstract

Chlamydia trachomatis is an obligate intracellular pathogen and the world's leading cause of preventable infectious blindness and bacterial sexually transmitted infections. Due to the high prevalence of chlamydial infections along with negative effects of current broad-spectrum treatment strategies, new antichlamydial agents with novel targets are desperately needed.

Funder

Deutsche Forschungsgemeinschaft

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00075-23

Reference86 articles.

1. Staphylococcus aureus ClpC Is Required for Stress Resistance, Aconitase Activity, Growth Recovery, and Death

2. ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells