Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase-2 Inhibitor with a Phenylbenzamide–Pentapeptide Hybrid Scaffold
Author:
Affiliation:
1. Taisho Pharmaceutical Co., Ltd., Saitama331-9530, Japan
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01698
Reference55 articles.
1. Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models
2. Matrix metalloproteinase degradation of extracellular matrix: biological consequences
3. Matrix Metalloproteinases as New Targets in Alzheimer’s Disease: Opportunities and Challenges
4. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
5. Physiology and pathophysiology of matrix metalloproteases
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