Discovery of Novel Indazole Chemotypes as Isoform-Selective JNK3 Inhibitors for the Treatment of Parkinson’s Disease-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Discovery of Novel Indazole Chemotypes as Isoform-Selective JNK3 Inhibitors for the Treatment of Parkinson’s Disease

Published:2023-01-17 Issue:2 Volume:66 Page:1273-1300
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shuai Wen¹,Bu Faqian¹,Zhu Yumeng¹,Wu Yongya¹,Xiao Huan¹,Pan Xiaoli¹,Zhang Jifa¹^ORCID,Sun Qiu¹,Wang Guan¹^ORCID,Ouyang Liang¹^ORCID

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, National Clinical Research Center for Geriatrics, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China

Funder

Chinese Academy of Medical Sciences

Central University Basic Research Fund of China

Natural Science Foundation of Sichuan Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01410

Reference63 articles.

1. Function and therapeutic value of astrocytes in neurological diseases

2. Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease

3. Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease

4. Map kinase signaling as therapeutic target for neurodegeneration

5. Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Update on JNK inhibitor patents: 2015 to present;Expert Opinion on Therapeutic Patents;2024-09-08

2. Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases;ACS Chemical Neuroscience;2024-04-22

3. Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives;European Journal of Medicinal Chemistry;2023-12

4. Discovery of a Dual Tubulin and Neuropilin-1 (NRP1) Inhibitor with Potent In Vivo Anti-Tumor Activity via Pharmacophore-based Docking Screening, Structure Optimization, and Biological Evaluation;Journal of Medicinal Chemistry;2023-11-24

5. Novel Tryptanthrin Derivatives with Selectivity as c–Jun N–Terminal Kinase (JNK) 3 Inhibitors;Molecules;2023-06-16

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3