Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors-Reference-Cited by-全球学者库

Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors

Published:2022-11-10 Issue:22 Volume:65 Page:15374-15390
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chan Shingpan¹,Zhang Yunong¹,Wang Jie¹^ORCID,Yu Qiuchun¹,Peng Xia²,Zou Jian¹,Zhou Licheng³,Tan Li¹,Duan Yunxin¹,Zhou Yang¹^ORCID,Hur Hoon⁴,Ai Jing²,Wang Zhen³^ORCID,Ren Xiaomei³,Zhang Zhang¹^ORCID,Ding Ke¹³⁵^ORCID

Affiliation:

1. International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, #855 Xingye Avenue, Guangzhou 510632, China

2. Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, Shanghai 201203, China

3. State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

4. Department of Surgery, Ajou University School of Medicine, 164 Worldcup-ro, Yeongtong-gu, Suwon-si 16499, Gyeonggi-do, Republic of Korea

5. The First Affiliated Hospital (Huaqiao Hospital), Jinan University, #601 Huangpu Avenue West, Guangzhou 510632, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Shanghai Municipal Commission of Health and Family Planning

State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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