Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance-Reference-Cited by-同舟云学术

Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance

Published:2022-06-30 Issue:13 Volume:65 Page:8998-9010
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Colini Baldeschi Arianna¹^ORCID,Zattoni Marco¹,Vanni Silvia¹,Nikolic Lea¹,Ferracin Chiara¹,La Sala Giuseppina²,Summa Maria³,Bertorelli Rosalia³,Bertozzi Sine Mandrup⁴,Giachin Gabriele⁵^ORCID,Carloni Paolo⁶⁷⁸^ORCID,Bolognesi Maria Laura⁹^ORCID,De Vivo Marco²^ORCID,Legname Giuseppe¹^ORCID

Affiliation:

1. Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy

2. Molecular Modeling & Drug Discovery Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy

3. Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy

4. Analytical Chemistry Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy

5. Department of Chemical Sciences (DiSC), University of Padua, Via F. Marzolo 1, 35131 Padova, Italy

6. Institute for Advanced Simulations (IAS)-5/Institute for Neuroscience and Medicine (INM)-9, “Computational Medicine”, Forschungszentrum Jülich, 52428 Jülich, Germany

7. Institute for Neuroscience and Medicine (INM)-11, “Molecular Neuroscience and Neuroimaging”, Forschungszentrum Jülich, 52428 Jülich, Germany

8. Department of Physics, RWTH-Aachen University, 52074 Aachen, Germany

9. Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy

Funder

Scuola Internazionale Superiore di Studi Avanzati

Helmholtz Association

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00205