Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues

Author:

Kim Dong Hwan1,Kim Jaehyeon1,Lee Hakmin1,Lee Dongyun1,Im So Myoung1,Kim Ye Eun1,Yoo Miryeong1,Cheon Yong-Pil2,Bartz Jason C.3,Son Young-Jin4,Choi Eun-Kyoung56,Kim Yong-Sun5,Jeon Jae-Ho1,Kim Hyo Shin1,Lee Sungeun1,Ryou Chongsuk1,Nam Tae-gyu1

Affiliation:

1. Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea

2. Division of Developmental Biology and Physiology, Department of Biotechnology, Sungshin University, Seoul, Korea

3. Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, NE, USA

4. Department of Pharmacy, Sunchon National University, Suncheon, Republic of Korea

5. Ilsong Institute of Life Science, Hallym University, Seoul, Republic of Korea

6. Department of Biomedical Gerontology, Graduate School of Hallym University, Chuncheon, Korea

Funder

Institute of Information & communications Technology Planning & Evaluation

Korea government

Artificial Intelligence Convergence Research Center (Hanyang University ERICA]

Korea Health Technology R&D

Korea Health Industry Development Institute

Ministry of Health & Welfare, Republic of Korea

Basic Science Research Program through the National Research Foundation of Korea

Ministry of Education

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference54 articles.

1. Nobel Lecture: Prions

2. Prions and prion diseases: fundamentals and mechanistic details;Ryou C.;J Microbiol Biotechnol,2007

3. The Priori Diseases

4. Neuropathology of Human Prion Diseases

5. Loss of PIKfyve drives the spongiform degeneration in prion diseases

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