[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis-Reference-Cited by-同舟云学术

[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis

Published:2020-02-04 Issue:5 Volume:63 Page:2511-2526
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Childress Elizabeth S.¹,Salamoun Joseph M.¹,Hargett Stefan R.²,Alexopoulos Stephanie J.³,Chen Sing-Young³,Shah Divya P.³,Santiago-Rivera José¹,Garcia Christopher J.¹,Dai Yumin¹^ORCID,Tucker Simon P.⁴⁵,Hoehn Kyle L.²³,Santos Webster L.¹^ORCID

Affiliation:

1. Department of Chemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, United States

2. Departments of Pharmacology and Medicine, University of Virginia, Charlottesville, Virginia 22908, United States

3. School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, NSW 2033, Australia

4. Continuum Biosciences, Pty Ltd., 2035 Sydney, Australia

5. Continuum Biosciences Inc., Boston, Massachusetts 02116, United States

Funder

Virginia Biosciences Health Research Corporation

Commonwealth of Virginia?s Alzheimer?s and Related Diseases Research Award Fund

Continuum Biosciences, Inc.

Publisher

American Chemical Society (ACS)