Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity-Reference-Cited by-同舟云学术

Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity

Published:2023-03-07 Issue:6 Volume:66 Page:3876-3895
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Murray Jacob H.¹,Burgio Ariel L.¹,Beretta Martina²,Hargett Stefan R.³,Harris Thurl E.³^ORCID,Olzomer Ellen²,Grams R. Justin¹^ORCID,Garcia Christopher J.¹,Li Catherine²,Salamoun Joseph M.¹,Hoehn Kyle L.²³,Santos Webster L.¹^ORCID

Affiliation:

1. Department of Chemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, United States

2. School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, New South Wales 2033, Australia

3. Department of Pharmacology, University of Virginia, Charlottesville, Virginia 22908, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Health and Medical Research Council

Virginia Biosciences Health Research Corporation

Continuum Biosciences, Inc.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01573

Reference55 articles.

1. American Association of Clinical Endocrinologists’ Position Statement on Obesity and Obesity Medicine

2. Obesity as a Disease: The Obesity Society 2018 Position Statement

3. Obesity I: Overview and molecular and biochemical mechanisms

4. Obesity, Inflammation, and Cardiovascular Risk

5. Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and anti-proliferative effect of novel 4-Aryl-1, 3-Thiazole-TPP conjugates via mitochondrial uncoupling process;Bioorganic Chemistry;2024-09

2. Drug targets regulate systemic metabolism and provide new horizons to treat nonalcoholic steatohepatitis;Metabolism Open;2024-03

3. Conjugating uncoupler compounds with hydrophobic hydrocarbon chains to achieve adipose tissue selective drug accumulation;Scientific Reports;2024-02-28

4. Synthesis and Anti-Proliferative Effect of Novel 4-Aryl-1, 3-Thiazole-Tpp Conjugates Via Mitochondrial Uncoupling Process;2024

5. PTPN2 regulates metabolic flux to affect beta cell susceptibility to inflammatory stress;Diabetes;2023-11-28