4,8-Dimethylcoumarin Inhibitors of Intestinal Anion Exchanger slc26a3 (Downregulated in Adenoma) for Anti-Absorptive Therapy of Constipation-Reference-Cited by-同舟云学术

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4,8-Dimethylcoumarin Inhibitors of Intestinal Anion Exchanger slc26a3 (Downregulated in Adenoma) for Anti-Absorptive Therapy of Constipation

Published:2019-08-07 Issue:17 Volume:62 Page:8330-8337
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lee Sujin^ORCID,Cil Onur,Haggie Peter M.,Verkman Alan S.^ORCID

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

University of California Drug Discovery Consortium

Clinical and Translational Science Institute, University of California San Francisco

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01192

Reference28 articles.

1. Diagnosis and management of chronic constipation in adults

2. Chronic constipation

3. Existing and emerging therapies for managing constipation and diarrhea

4. CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. DRA involvement in linaclotide-stimulated bicarbonate secretion during loss of CFTR function;JCI Insight;2024-06-13

2. Substituted 4-methylcoumarin inhibitors of SLC26A3 (DRA) for treatment of constipation and hyperoxaluria;RSC Medicinal Chemistry;2024

3. Nourishing Yin and moistening dryness formula inhibits colon cell apoptosis via activating the PI3K/AKT signaling pathway to ameliorate Yin-deficiency constipation in mice;Journal of Functional Foods;2023-11

4. Critical role of down-regulated in adenoma bicarbonate transporter in linaclotide stimulated intestinal bicarbonate secretion;2023-05-07

5. Small molecule inhibitors of intestinal epithelial anion exchanger SLC26A3 (DRA) with a luminal, extracellular site of action;European Journal of Medicinal Chemistry;2023-03

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