Substituted 4-methylcoumarin inhibitors of SLC26A3 (DRA) for treatment of constipation and hyperoxaluria-Reference-Cited by-同舟云学术

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Substituted 4-methylcoumarin inhibitors of SLC26A3 (DRA) for treatment of constipation and hyperoxaluria

Published:2024 Issue:5 Volume:15 Page:1731-1736
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Ahmadi Maria¹,de Souza Goncalves Livia²^ORCID,Verkman Alan S.³,Cil Onur²^ORCID,Anderson Marc O.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA, USA

2. Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA

3. Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

Abstract

Substituted 4-methylcoumarins were found to be active against SLC26A3 (DRA) using in vitro and in vivo assays.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

University of California, San Francisco

Cystic Fibrosis Foundation

National Eye Institute

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00644A

Reference27 articles.

1. Diagnosis and management of chronic constipation in adults

2. Existing and emerging therapies for managing constipation and diarrhea

3. Chronic constipation

4. Epidemiology of stone disease across the world

5. Prevalence of Kidney Stones in the United States

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