Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators
Author:
Affiliation:
1. Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, United States
2. Duke University Medical Center, Durham, North Carolina 27709, United States
Funder
National Institute on Drug Abuse
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00340
Reference28 articles.
1. The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami
2. DISTRIBUTION OF NEUROTENSIN AND ITS RECEPTOR IN THE CENTRAL NERVOUS SYSTEM
3. Distribution of Neurotensin Receptors in Mammalian Brain.
4. Neurotensin and neurotensin receptors
5. Mechanisms of Regulation of Neurotensin Receptors
Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays;Journal of Medicinal Chemistry;2024-09-11
2. Hungry for relief: Potential for neurotensin to address comorbid obesity and pain;Appetite;2024-09
3. Molecular glues as potential GPCR therapeutics;Biochemical Pharmacology;2024-06
4. Development of a Fluorescent Ligand for the Intracellular Allosteric Binding Site of the Neurotensin Receptor 1;ACS Pharmacology & Translational Science;2024-04-18
5. Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens;Neuropharmacology;2023-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3