Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design

Author:

Levy Nicolas12,Bruneau Jean-Michel1,Le Rouzic Erwann1,Bonnard Damien1,Le Strat Frédéric1,Caravano Audrey1,Chevreuil Francis1,Barbion Julien1,Chasset Sophie1,Ledoussal Benoît1,Moreau François1,Ruff Marc2ORCID

Affiliation:

1. Mutabilis, 102 Avenue Gaston Roussel, 93230 Romainville, France

2. IGBMC, 1 Rue Laurent Fries, 67404 Illkirch, France

Funder

Seventh Framework Programme

Innovative Medicines Initiative

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference57 articles.

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2. O’Neill, J., Chair. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations; Review on Antimicrobial Resistance; HM Government, 2014; p 4, https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf (accessed Jun 15, 2018).

3. Antimicrobial Resistance Benchmark 2018: Methodology; Access to Medicine Foundation: Amsterdam, The Netherlands, 2018; pp 1–41.

4. WHO. List of Bacteria for Which New Antibiotics are Urgently Needed. http://www.who.int/news-room/detail/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed (accessed June 10, 2018).

5. Morphogenesis of rod-shaped sacculi

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