Emerging siRNA Design Principles and Consequences for Biotransformation and Disposition in Drug Development-Reference-Cited by-同舟云学术

Emerging siRNA Design Principles and Consequences for Biotransformation and Disposition in Drug Development

Author:

Humphreys Sara C.¹^ORCID,Thayer Mai B.¹,Campbell Jabbar²,Chen Wen Li Kelly³,Adams Dan³,Lade Julie M.¹,Rock Brooke M.¹

Affiliation:

1. Pharmacokinetics and Drug Metabolism Department, Amgen Research, 1120 Veterans Boulevard, South San Francisco, California 94080, United States

2. Neuroscience Department, Amgen Research, 360 Binney Street, Cambridge, Massachusetts 02141, United States

3. Comparative Biology and Safety Sciences Department, Amgen Research, 360 Binney Street, Cambridge, Massachusetts 02141, United States

Funder

Amgen

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

Reference139 articles.

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

4. DeepSipred: A deep-learning-based approach on siRNA inhibition prediction;Proceedings of the 2024 4th International Conference on Bioinformatics and Intelligent Computing;2024-01-26