Structure–Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties

Author:

Chen Hao1,Deng Shanshan1,Wang Yuxi2,Albadari Najah1,Kumar Gyanendra3,Ma Dejian1,Li Weimin2,White Stephen W.3,Miller Duane D.1ORCID,Li Wei1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

3. Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

Funder

National Cancer Institute

National Center for Research Resources

University of Tennessee

Office of the Director

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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