Structure–Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties-Reference-Cited by-同舟云学术

Structure–Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties

Published:2019-12-20 Issue:2 Volume:63 Page:827-846
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Hao¹,Deng Shanshan¹,Wang Yuxi²,Albadari Najah¹,Kumar Gyanendra³,Ma Dejian¹,Li Weimin²,White Stephen W.³,Miller Duane D.¹^ORCID,Li Wei¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

3. Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

Funder

National Cancer Institute

National Center for Research Resources

University of Tennessee

Office of the Director

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01815

Reference39 articles.

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4. Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton

5. Structural Plasticity in Actin and Tubulin Polymer Dynamics

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