Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors-Reference-Cited by-同舟云学术

Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors

Published:2019-06-09 Issue:13 Volume:62 Page:6137-6145
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhan Wenhu¹,Visone Joseph¹²,Ouellette Tierra¹,Harris Jacob C.¹²,Wang Rong³,Zhang Hao¹,Singh Pradeep K.⁴,Ginn John⁵,Sukenick George³,Wong Tzu-Tshin⁶,Okoro Judith I.⁷,Scales Ryan M.⁸,Tumwebaze Patrick K.⁷,Rosenthal Philip J.⁹,Kafsack Björn F. C.¹,Cooper Roland A.¹⁰,Meinke Peter T.⁵,Kirkman Laura A.¹²,Lin Gang¹^ORCID

Affiliation:

1. Department of Microbiology & Immunology, Weill Cornell Medicine, 1300 York Avenue, New York, New York 10065, United States

2. Department of Medicine, Division of Infectious Diseases, 1300 York Avenue, New York, New York 10065, United States

3. NMR Analytical Core Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, United States

4. Chemical Core Facility, Department of Biochemistry, Weill Cornell Medicine, New York, New York 10065, United States

5. Tri-Institutional Therapeutics Discovery Institute, 413 E. 69th Street, New York, New York 10065, United States

6. Takeda Pharmaceutical Company Ltd., 35 Landsdowne Street, Cambridge, Massachusetts 02139, United States

7. Infectious Diseases Research Collaboration, Kampala, Uganda

8. Department of Public Health, University of North Carolina, Charlotte, North Carolina 28223, United States

9. Department of Medicine, University of California, San Francisco, San Francisco, California 94143, United States

10. Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States

Funder

National Cancer Institute

National Institute of Allergy and Infectious Diseases

Medicines for Malaria Venture

Cornell University

National Institute on Minority Health and Health Disparities

Tri-Institutional Therapeutics Discovery Institute

Weill Medical College, Cornell University

Department of Medicine, Weill Cornell Medicine Seed fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00363

Reference31 articles.

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2. WHO. World Malaria Report 2018; World Health Organization: Geneva, 2018.

3. Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

4. Artemisinin resistance on the Thai–Cambodian border

5. The interplay between drug resistance and fitness in malaria parasites

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