l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ-Reference-Cited by-同舟云学术

l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ

Published:2020-05-01 Issue:13 Volume:63 Page:6727-6740
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gellrich Leonie¹,Heitel Pascal¹^ORCID,Heering Jan²,Kilu Whitney¹,Pollinger Julius¹,Goebel Tamara¹,Kahnt Astrid¹,Arifi Silvia¹,Pogoda Werner³,Paulke Alexander³,Steinhilber Dieter¹²,Proschak Ewgenij¹²^ORCID,Wurglics Mario¹,Schubert-Zsilavecz Manfred¹,Chaikuad Apirat¹⁴^ORCID,Knapp Stefan¹⁴^ORCID,Bischoff Iris⁵,Fürst Robert⁵,Merk Daniel¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, D-60438 Frankfurt, Germany

2. Branch for Translational Medicine and Pharmacology TMP, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Theodor-Stern-Kai 7, D-60596 Frankfurt, Germany

3. Department of Forensic Toxicology, Institute of Forensic Medicine, Goethe University Frankfurt, Kennedyallee 104, D-60596 Frankfurt, Germany

4. Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University Frankfurt, Max-von-Laue-Straße 15, D-60438 Frankfurt, Germany

5. Institute of Pharmaceutical Biology, Goethe University Frankfurt, Max-von-Laue-Str. 9, D-60438 Frankfurt, Germany

Funder

Merck

Bayer

Merck KGaA

Pfizer

Ontario Ministry of Economic Development and Innovation

Innovative Medicines Initiative

Genome Canada

AbbVie

Funda????o de Amparo ?? Pesquisa do Estado de S??o Paulo

Boehringer Ingelheim