Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases

Author:

Pemberton Orville A.1,Jaishankar Priyadarshini2,Akhtar Afroza1,Adams Jessie L.3,Shaw Lindsey N.3ORCID,Renslo Adam R.2ORCID,Chen Yu1ORCID

Affiliation:

1. Department of Molecular Medicine, University of South Florida Morsani College of Medicine, 12901 Bruce B. Downs Boulevard, MDC 3522, Tampa, Florida 33612, United States

2. Department of Pharmaceutical Chemistry and Small Molecule Discovery Center, University of California, San Francisco, 600 16th Street, Genentech Hall N574, San Francisco, California 94158, United States

3. Department of Cell Biology, Microbiology & Molecular Biology, University of South Florida, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States

Funder

National Center for Advancing Translational Sciences

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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