Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers-Reference-Cited by-同舟云学术

Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers

Published:2011-01-13 Issue:4 Volume:54 Page:1022-1032
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Abate Carmen¹,Niso Mauro¹,Lacivita Enza¹,Mosier Philip D.²,Toscano Annamaria¹,Perrone Roberto¹

Affiliation:

1. Dipartimento Farmacochimico, Università degli Studi di Bari ALDO MORO, Via Orabona 4, I-70125 Bari, Italy

2. Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1013133

Reference48 articles.

1. Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

2. Sigma-1 Receptor Chaperones and Diseases

3. σ-1 Receptors (σ1Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export

4. Sigma-1 Receptors Bind Cholesterol and Remodel Lipid Rafts in Breast Cancer Cell Lines

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