Synthesis of 2α-Heteroarylalkyl Active Vitamin D3 with Therapeutic Effect on Enhancing Bone Mineral Density in Vivo-Reference-Cited by-同舟云学术

Synthesis of 2α-Heteroarylalkyl Active Vitamin D3 with Therapeutic Effect on Enhancing Bone Mineral Density in Vivo

Published:2013-05-31 Issue:7 Volume:4 Page:671-674
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Matsuo Miki¹,Hasegawa Asami¹,Takano Masashi¹,Saito Hiroshi²,Kakuda Shinji²,Chida Takayuki²,Takagi Ken-ichiro²,Ochiai Eiji²,Horie Kyohei²,Harada Yoshifumi²,Takimoto-Kamimura Midori²,Takenouchi Kazuya²,Sawada Daisuke¹,Kittaka Atsushi¹

Affiliation:

1. Faculty of Pharmaceutical Sciences, Teikyo University, Itabashi-ku, Tokyo 173-8605, Japan

2. Teijin Institute for Bio-medical Research, Teijin Pharma Ltd., Hino-shi, Tokyo 191-8512, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml400098w

Reference14 articles.

1. The nuclear receptor superfamily: The second decade

2. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

3. The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

4. Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Substituted Analogues

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