Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo-Reference-Cited by-同舟云学术

Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo

Published:2021-04-24 Issue:9 Volume:64 Page:5689-5709
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kawagoe Fumihiro¹,Mendoza Aileen²,Hayata Yuki³,Asano Lisa²,Kotake Kenjiro²,Mototani Sayuri¹,Kawamura Satoshi³,Kurosaki Shigeyuki³,Akagi Yusuke⁴,Takemoto Yasushi²,Nagasawa Kazuo⁴^ORCID,Nakagawa Hayato³,Uesugi Motonari²⁵⁶^ORCID,Kittaka Atsushi¹^ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan

2. Institute for Chemical Research and Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Uji, Kyoto 611-0011, Japan

3. Department of Gastroenterology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

4. Department of Biotechnology and Life Sciences, Graduate School of Technology, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan

5. AMED-CREST, Japan Agency for Medical Research and Development, 1-7-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan

6. School of Pharmacy, Fudan University, Shanghai 201203, China

Funder

Core Research for Evolutional Science and Technology

Japan Agency for Medical Research and Development

Institute for Chemical Research, Kyoto University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02179