Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists-Reference-Cited by-同舟云学术

Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists

Published:2004-12-21 Issue:2 Volume:48 Page:353-356
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cole Derek C.¹,Lennox William J.¹,Lombardi Sabrina¹,Ellingboe John W.¹,Bernotas Ronald C.¹,Tawa Gregory J.¹,Mazandarani Hossein¹,Smith Deborah L.¹,Zhang Guoming¹,Coupet Joseph¹,Schechter Lee E.¹

Affiliation:

1. Chemical and Screening Sciences, Wyeth Research, 401 N. Middletown Road, Pearl River, New York 10965, Chemical and Screening Sciences, Wyeth Research, 500 Arcola Road, Collegeville, Pennsylvania 19426, Chemical and Screening Sciences, Wyeth Research, Princeton, New Jersey 08852, and Neurosciences, Wyeth Research, Princeton, New Jersey 08852

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049243i

Reference21 articles.

1. A Novel Rat Serotonin (5-HT6) Receptor: Molecular Cloning, Localization and Stimulation of cAMP Accumulation

2. 5-HT6 receptors positively coupled to adenylyl cyclase in striatal neurones in culture

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