Biased Profile of Xanomeline at the Recombinant Human M<sub>4</sub> Muscarinic Acetylcholine Receptor-Reference-Cited by-同舟云学术

Biased Profile of Xanomeline at the Recombinant Human M₄ Muscarinic Acetylcholine Receptor

Published:2022-04-05 Issue:8 Volume:13 Page:1206-1218
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

McDonald Jack K.¹,van der Westhuizen Emma T.¹,Pham Vi¹,Thompson Geoff¹,Felder Christian C.²,Paul Steven M.²,Thal David M.¹³^ORCID,Christopoulos Arthur¹³,Valant Celine¹³^ORCID

Affiliation:

1. Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

2. Karuna Therapeutics, Boston, Massachusetts 02110, United States

3. Neuromedicines Discovery Centre, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

Funder

National Health and Medical Research Council

Australian Research Council

Wellcome Trust

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00827

Reference61 articles.

1. Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia

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