Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR

Published:2023-10 Issue: Volume:258 Page:115588
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Jörg Manuela,van der Westhuizen Emma T.,Lu Yao,Christopher Choy K.H.,Shackleford David M.,Khajehali Elham,Tobin Andrew B.,Thal David M.,Capuano Ben,Christopoulos Arthur,Valant Celine,Scammells Peter J.^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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1. Discovery of 2-Methyl-5-(1H-pyrazol-4-yl)pyridines and Related Heterocycles as Promising M₄ mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders;Journal of Medicinal Chemistry;2024-07-18