Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons-Reference-Cited by-同舟云学术

Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons

Published:2021-08-03 Issue:16 Volume:12 Page:3049-3059
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Rodriguez Yssa A.¹,Kaur Sukmanjit¹,Nolte Erika¹,Zheng Zhang²,Blagg Brian S. J.²^ORCID,Dobrowsky Rick T.¹^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, University of Kansas, 5064 Malott Hall/1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States

2. Department of Chemistry and Biochemistry University of Notre Dame, 305 McCourtney Hall, Notre Dame, Indiana 46556, United States

Funder

National Institute of Neurological Disorders and Stroke

Division of Cancer Prevention, National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00340

Reference46 articles.

1. New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain

2. Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

3. Mitochondrial stress and the pathogenesis of diabetic neuropathy

4. The role of aberrant mitochondrial bioenergetics in diabetic neuropathy

5. Synthesis and Evaluation of Novologues as C-Terminal Hsp90 Inhibitors with Cytoprotective Activity against Sensory Neuron Glucotoxicity

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