Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer’s Disease Brain

Author:

Michno Wojciech1234,Bowman Andrew5,Jha Durga1,Minta Karolina1,Ge Junyue1,Koutarapu Srinivas1,Zetterberg Henrik16789,Blennow Kaj161011,Lashley Tammaryn712,Heeren Ron M. A.5ORCID,Hanrieder Jörg16713ORCID

Affiliation:

1. Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal 43180, Sweden

2. Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E6BT, United Kingdom

3. Department of Public Health and Caring Sciences, Uppsala University, Uppsala 75237, Sweden

4. Science for Life Laboratory (SciLife), Uppsala University, Uppsala 75237, Sweden

5. Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University, Maastricht 6229 ER, The Netherlands

6. Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 43180, Sweden

7. Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom

8. UK Dementia Research Institute at UCL, London WC1E 6BT, United Kingdom

9. Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong 999077, China

10. Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris 75005, France

11. Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei 230001, P. R. China

12. Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London WC1N 1PJ, United Kingdom

13. Science for Life Laboratory (SciLife), University of Gothenburg, Gothenburg 40530, Sweden

Funder

Vetenskapsr?det

National Institute on Aging

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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