1. Department of Anesthesiology & Critical Care, University of Pennsylvania Perelman School of Medicine, 3620 Hamilton Walk, Philadelphia, Pennsylvania 19104, United States
2. Epigenetics Institute, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States
3. Center for Computational and Integrative Biology, Department of Physics, Rutgers University, Camden, New Jersey 08102, United States
4. Department of Chemistry, University of Pennsylvania School of Arts and Sciences, 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States