Ketamine Metabolite (2R,6R)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors-Reference-Cited by-同舟云学术

Ketamine Metabolite (2R,6R)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors

Published:2021-04-27 Issue:9 Volume:12 Page:1487-1497
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Joseph Thomas T.¹^ORCID,Bu Weiming¹,Lin Wenzhen¹²,Zoubak Lioudmila³,Yeliseev Alexei³,Liu Renyu¹,Eckenhoff Roderic G.¹,Brannigan Grace⁴^ORCID

Affiliation:

1. Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, Guangxi 530021, China

3. National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852, United States

4. Center for Computational and Integrative Biology and Department of Physics, Rutgers University, Camden, New Jersey 08102, United States

Funder

Foundation for Anesthesia Education and Research

National Institute on Alcohol Abuse and Alcoholism

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00741

Reference60 articles.

1. Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism

2. Opioid system is necessary but not sufficient for antidepressive actions of ketamine in rodents

3. Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC

4. Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

5. EVIDENCE FOR DIRECT INTERACTION OF KETAMINE WITH ?- AND ?2-ADRENOCEPTORS

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