Biophysical and in Vivo Studies Identify a New Natural-Based Polyphenol, Counteracting Aβ Oligomerization in Vitro and Aβ Oligomer-Mediated Memory Impairment and Neuroinflammation in an Acute Mouse Model of Alzheimer’s Disease-Reference-Cited by-同舟云学术

Biophysical and in Vivo Studies Identify a New Natural-Based Polyphenol, Counteracting Aβ Oligomerization in Vitro and Aβ Oligomer-Mediated Memory Impairment and Neuroinflammation in an Acute Mouse Model of Alzheimer’s Disease

Published:2019-10-11 Issue:11 Volume:10 Page:4462-4475
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Tomaselli Simona¹^ORCID,La Vitola Pietro²,Pagano Katiuscia¹,Brandi Edoardo²,Santamaria Giulia²,Galante Denise³,D’Arrigo Cristina³,Moni Lisa⁴^ORCID,Lambruschini Chiara⁴,Banfi Luca⁴^ORCID,Lucchetti Jacopo⁵,Fracasso Claudia⁵,Molinari Henriette¹^ORCID,Forloni Gianluigi²,Balducci Claudia²,Ragona Laura¹^ORCID

Affiliation:

1. Istituto per lo Studio delle Macromolecole (ISMAC), CNR, Milan 20133, Italy

2. Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy

3. Istituto per lo Studio delle Macromolecole (ISMAC), CNR, Genoa 16149, Italy

4. Department of Chemistry and Industrial Chemistry, Università di Genova, Genova 16146, Italy

5. Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy

Funder

Alzheimer's Association

Fondazione Cariplo

Fondazione Antonio de Marco

Publisher

American Chemical Society (ACS)