Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity-Reference-Cited by-同舟云学术

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

Published:2011-03-07 Issue:12 Volume:133 Page:4348-4358
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Hochdörffer Katrin¹,März-Berberich Julia¹,Nagel-Steger Luitgard²,Epple Matthias¹,Meyer-Zaika Wolfgang¹,Horn Anselm H.C.³,Sticht Heinrich³,Sinha Sharmistha,Bitan Gal,Schrader Thomas¹

Affiliation:

1. Universität Duisburg-Essen, Fachbereich Chemie, Universitätstrasse 5, 45117 Essen, Germany

2. Universität Düsseldorf, Fachbereich Biologie, Universitätsstrasse 1, 40225 Düsseldorf, Germany

3. Universität Erlangen-Nürnberg, Institut für Biochemie, Fahrstrasse 17, 91054 Erlangen, Germany

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja107675n

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3. Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism

4. Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

5. Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

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