Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

Author:

Sampaio-Dias Ivo E.1ORCID,Rodríguez-Borges José E.1,Yáñez-Pérez Víctor2,Arrasate Sonia3ORCID,Llorente Javier34,Brea José M.5,Bediaga Harbil26,Viña Dolores78,Loza María Isabel5,Caamaño Olga9,García-Mera Xerardo9,González-Díaz Humberto21011ORCID

Affiliation:

1. LAQV/REQUIMTE, Dept. of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal

2. Dept. of Organic Chemistry II, University of Basque Country (UPV-EHU), 48940 Leioa, Spain

3. Dept. of Pharmacology, Faculty of Medicine and Nursing, University of Basque Country (UPV-EHU), 48940 Leioa, Spain

4. Dept. of Pharmacology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

5. Innopharma Screening Platform, Biofarma Research group, Centre of Research in Molecular Medicine and Chronic Diseases CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

6. Dept. of Physical Chemistry, University of Basque Country (UPV-EHU), 48940 Leioa, Spain

7. Dept. of Pharmacology, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

8. Centre of Research in Molecular Medicine and Chronic Diseases CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

9. Dept. of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

10. Basque Center for Biophysics (CSIC UPV/EHU), University of Basque Country (UPV-EHU), 48940 Leioa, Spain

11. IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain

Funder

European Regional Development Fund

Ministerio de Econom?a y Competitividad

Ikerbasque, Basque Foundation for Science

Eusko Jaurlaritza

Xunta de Galicia

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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