Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D<sub>2</sub> Receptors-Reference-Cited by-同舟云学术

Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D₂ Receptors

Published:2023-11-14 Issue:12 Volume:14 Page:1656-1663
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Silva-Reis Sara C.¹²^ORCID,Correia Xavier C.¹²^ORCID,Costa-Almeida Hugo F.¹²^ORCID,Pires-Lima Beatriz L.¹^ORCID,Maronde Daiane¹,Costa Vera M.²³^ORCID,García-Mera Xerardo⁴,Cruz Luís¹^ORCID,Brea José⁵^ORCID,Loza María Isabel⁵^ORCID,Rodríguez-Borges José E.¹,Sampaio-Dias Ivo E.¹^ORCID

Affiliation:

1. LAQV/REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal

2. UCIBIO/REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal

3. Associate Laboratory i4HB - Institute for Health and Bioeconomy, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal

4. Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, E-15782 Santiago de Compostela, Spain

5. Innopharma Screening Platform, Biofarma Research group, Centre of Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, E-15782 Santiago de Compostela, Spain

Funder

Xunta de Galicia

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00264

Reference67 articles.

1. Regulation of Formation and Proposed Structure of the Factor Inhibiting the Release of Melanocyte-Stimulating Hormone

2. Inhibition by L-Prolyl-L-Leucyl-Glycinamide (PLG) of Alpha-melanocyte stimulating hormone release from hypothalamic slices

3. Modulation of Agonist Binding to Human Dopamine Receptor Subtypes by l-Prolyl-l-leucyl-glycinamide and a Peptidomimetic Analog

4. Development of peptidomimetic ligands of Pro-Leu-Gly-NH2 as allosteric modulators of the dopamine D2 receptor

5. Interaction of l-Prolyl-l-Leucyl Glycinamide with Dopamine D2Receptor: Evidence for Modulation of Agonist Affinity States in Bovine Striatal Membranes

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