Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant-Reference-Cited by-同舟云学术

Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant

Published:2021-05-11 Issue:11 Volume:12 Page:1873-1884
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Rodriguez-Contreras Dayana¹,Condon Alec F.²^ORCID,Buck David C.³,Asad Naeem⁴,Dore Timothy M.⁴^ORCID,Verbeek Dineke S.⁵,Tijssen Marina A. J.⁶,Shinde Ujwal⁷,Williams John T.²^ORCID,Neve Kim A.¹^ORCID

Affiliation:

1. Research Service, VA Portland Health Care System, and Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon 97239, United States

2. Vollum Institute, Oregon Health & Science University, Portland, Oregon 97239, United States

3. Research Service, VA Portland Health Care System, Portland, Oregon 97239, United States

4. New York University Abu Dhabi, Saadiyat Island, PO Box 129188, Abu Dhabi, United Arab Emirates

5. Expertise Center Movement Disorders and Department of Genetics, University of Groningen, 9700 AB Groningen, The Netherlands

6. Expertise Center Movement Disorders and Department of Neurology, University of Groningen, 9700 AB Groningen, The Netherlands

7. Department of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, Oregon 97239, United States

Funder

National Institute of Neurological Disorders and Stroke

U.S. Department of Veterans Affairs

National Institute on Drug Abuse

New York University Abu Dhabi

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00712

Reference63 articles.

1. An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior

2. Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation

3. Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions

4. The role of dopamine in huntington's disease

5. Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds

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