Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds
Author:
Funder
NINDS
Publisher
Elsevier BV
Subject
Cell Biology
Reference132 articles.
1. Molecular biology of dopamine receptors
2. Developmental origins of brain disorders: roles for dopamine
3. New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy
4. Current perspectives on the selective regulation of dopamine D2 and D3 receptors
5. History of the Discovery of the Antipsychotic Dopamine D2 Receptor: A Basis for the Dopamine Hypothesis of Schizophrenia
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1. Recent Advances in representative small-molecule DRD2 inhibitors: Synthetic Routes and clinical applications;European Journal of Medicinal Chemistry;2024-11
2. A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site;Nature Communications;2024-09-05
3. Further exploration of N-4 substituents on the piperazine ring of the hybrid template 5/ 7-{[2-(4-Aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol and its analog: development of an exceptionally potent agonist for D2 & D3 receptors;Medicinal Chemistry Research;2024-08-08
4. Linkers in Bitopic Agonists Shape Bias Profile among Transducers for the Dopamine D2 and D3 Receptors;ACS Pharmacology & Translational Science;2024-07-26
5. Aromatic linker variations in novel dopamine D2 and D3 receptor ligands;Archiv der Pharmazie;2024-05-12
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