Further exploration of N-4 substituents on the piperazine ring of the hybrid template 5/ 7-{[2-(4-Aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol and its analog: development of an exceptionally potent agonist for D2 & D3 receptors
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Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00044-024-03291-3.pdf
Reference38 articles.
1. Emilien G, Maloteaux J-M, Geurts M, Hoogenberg K, Cragg S. Dopamine receptors-physiological understanding to therapeutic intervention potential. Pharmacol Therapeutics. 1999;84:133–56.
2. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiol Rev. 1998;78:189–225.
3. Das B, Modi G, Dutta A. Dopamine d3 agonists in the treatment of Parkinson’s disease. Curr Top Med Chem. 2015;15:908–26.
4. Li C, Biswas S, Li X, Dutta AK, Le W. Novel D3 dopamine receptor-preferring agonist D-264: Evidence of neuroprotective property in Parkinson’s disease animal models induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and lactacystin. J Neurosci Res. 2010;88:2513–23. https://doi.org/10.1002/jnr.22405.
5. Keck TM, John WS, Czoty PW, Nader MA, Newman AH. Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. J Med Chem. 2015;58:5361–80. https://doi.org/10.1021/jm501512b.
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