(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer’s Disease-Reference-Cited by-同舟云学术

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer’s Disease

Published:2021-04-02 Issue:8 Volume:12 Page:1328-1342
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Ismaili Lhassane¹^ORCID,Monnin Julie¹,Etievant Adeline¹,Arribas Raquel L.²³,Viejo Lucía²³,Refouvelet Bernard¹,Soukup Ondrej⁴^ORCID,Janockova Jana⁴,Hepnarova Vendula⁵,Korabecny Jan⁴,Kucera Tomas⁵,Jun Daniel⁵,Andrys Rudolf⁶,Musilek Kamil⁶^ORCID,Baguet Aurelie⁷,García-Frutos Eva M.⁸^ORCID,De Simone Angela⁹,Andrisano Vincenza⁹^ORCID,Bartolini Manuela¹⁰^ORCID,de los Ríos Cristóbal²³^ORCID,Marco-Contelles José¹¹^ORCID,Haffen Emmanuel¹

Affiliation:

1. Neurosciences intégratives et cliniques EA 481, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France

2. Servicio de Farmacología Clínica, Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa, C/Diego de León, 62, 28006 Madrid, Spain

3. Instituto Teofilo Hernando, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain

4. Biomedical Research Center, University Hospital Hradec Kralove, Czech Republic, University of Defence, 50003 Hradec Kralove, Czech Republic

5. Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, 66210 Brno, Czech Republic

6. Faculty of Science, Department of Chemistry, University Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic

7. Université Bourgogne Franche Comté, INSERM, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, F-25000 Besançon, France

8. Instituto de Ciencia de Materiales de Madrid, CSIC, Cantoblanco, 28049 Madrid, Spain

9. Department for Life Quality Studies, Alma Mater Studiorum University of Bologna, Corso di Augusto, 237, 47921 Rimini, Italy

10. Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy

11. Laboratory of Medicinal Chemistry, Instituto de Química Orgánica General, Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain

Funder

Ministerstvo ?kolstv?, Ml?de?e a Telov?chovy

Regional Council of Franche-Comt?

University Hospital Hradec Kralove

Long-term Development Plan, Faculty of Military Health Sciences

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00803

Reference70 articles.