Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson’s Disease or Schizophrenia-Reference-Cited by-同舟云学术

Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson’s Disease or Schizophrenia

Published:2019-01-04 Issue:5 Volume:10 Page:2222-2228
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Del Bello Fabio¹,Ambrosini Dario¹,Bonifazi Alessandro²,Newman Amy H.²^ORCID,Keck Thomas M.²³^ORCID,Giannella Mario¹,Giorgioni Gianfabio¹^ORCID,Piergentili Alessandro¹^ORCID,Cappellacci Loredana¹^ORCID,Cilia Antonio⁴,Franchini Silvia⁵^ORCID,Quaglia Wilma¹^ORCID

Affiliation:

1. Scuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino, Via S. Agostino 1, 62032 Camerino, Italy

2. Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse − Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States

3. Department of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States

4. Recordati S.p.A., Drug Discovery, Via Civitali 1, 20148 Milano, Italy

5. Dipartimento di Scienze della Vita, Università degli Studi di Modena e Reggio Emilia, Via Campi 103, 41125 Modena, Italy

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00677

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1. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia